As a general rule, a typical microdose is anywhere from 5 to 10 percent of a normal dose. For example, a typical dose of mushrooms is one to two grams. A microdose would be anywhere from 50 to 250 milligrams (or 0.05 to 0.25mg).

Through microdosing, you may feel a sense of calm energy, better focus, and a lighter mood. There should be no visual or physical side effects other than those mild enhancements.

Antidepressants can also nullify the effects of psychedelics.